alli FAQs

get answers to all of your questions

• Frequently Asked Questions

  • is alli safe?

    alli is the only FDA-approved over-the-counter weight loss aid. Since alli was made available over-the-counter in 2007, more than 10 million people worldwide have used the product. With more than 100 clinical studies involving 30,000 patients, orlistat is the most extensively studied weight loss drug in the world and continues to be a safe and effective product when used as directed to help people lose weight. More than 40 million people have used orlistat since it first became available in 1998.

  • does alli cause liver injury?

    FDA have concluded a review and stated that a cause and effect relationship has not been established. They also noted that out of a total of 13 cases of severe liver injury they identified, only one involved use of alli. 40 million patients and consumers have used orlistat since it first became available.

    alli is the only FDA-approved over-the-counter weight loss aid. Since alli was made available over-the-counter in 2007, more than 10 million people worldwide have used the product. With more than 100 clinical studies involving 30,000 patients, orlistat is the most extensively studied weight loss drug in the world and continues to be a safe and effective product when used as directed to help people lose weight. More than 40 million people have used orlistat since it first became available in 1998.

  • how does alli work?

    alli works by inhibiting some of the body’s absorption of dietary fat. Taken at meal times, it works by blocking the absorption of about 25% of fat in the foods you eat. Because of the way it works, alli must be used in conjunction with a reduced-calorie, low-fat diet containing about 15 grams of fat per meal. Eating a meal with too much fat while taking alli can result in bowel changes, such as loose stools, more frequent stools that may be hard to control, or gas with oily spotting. These changes, called treatment effects, may occur in the first weeks of treatment, are not harmful and can generally be managed by following a reduced-calorie, low-fat diet that does not exceed 15 grams of fat per meal.

    alli works in the gut; it is nonsystemically acting, which means it does not affect the central nervous system (CNS) and has no effect on the heart or the brain. Some weight-loss drugs and supplements that are systemically absorbed can be associated with CNS side effects (e.g., seizure, stroke and anxiety) or systemic side effects (e.g., heart palpitations, elevated blood pressure and heart problems). alli, a nonsystemic weight-loss aid, is not associated with these side effects, and its safety and efficacy are well established.

  • what are the side effects of alli?

    Most side effects are related to the way you take the product and how much fat you consume when taking alli. Not everyone experiences GI side effects (or “treatment effects”), but they can be manageable when you follow a reduced-calorie, low-fat diet.

    All drugs can have side effects and you should check with your doctor if anything unusual or severe occurs when using any weight-loss product. In controlled trials, only about 5% of subjects on alli dropped out due to treatment effects. In fact, anecdotally, many users have told us that treatment effects served as a signal that helped them adopt healthier eating patterns.

  • who can take alli?

    alli can be taken by overweight individuals age 18 or older who are ready to make the change to a reduced-calorie, low-fat diet. But, as with all medicines, there are some people who should not take alli or who need to check with their doctor first, so it is important to review the label before purchasing alli.

    alli has been studied in ethnically diverse populations and has been proven safe and effective for all populations regardless of gender, race and initial weight. Data shows that alli plus diet is always significantly better than diet alone.

  • how effective is alli?

    alli works by blocking the absorption of about 25% of fat in the foods you eat, leading to a 5% to 10% weight loss over time. alli met the rigorous FDA standards for a weight-loss aid. Clinical trials with alli have consistently shown it to be more effective than diet alone. alli can help people lose 50% more weight than with dieting alone. This means that if you could lose 10 pounds with a diet, you could lose 15 pounds working with alli.

  • how effective is the alli program?

    With alli, you can lose about 50% more weight than with just dieting alone. That means if you could lose 10 pounds through dieting alone, you could lose 15 with alli.

  • how does the alli program work?

    alli® is the only FDA-approved, over-the-counter weight-loss aid. But it’s more than just a pill. It’s an innovative weight-loss program.

    The pill works by preventing your body from absorbing some of the fat you eat. The active ingredient in alli attaches to some of the natural enzymes in the digestive system and prevents absorption of about a quarter of the fat you eat. Undigested fat cannot be absorbed and passes through the body naturally. Because alli works only in your digestive tract, it will not affect your heart or brain so you will not experience any racing heart or jitteriness.

    Along with the capsule, the alli program supplies you with a wealth of education, advice and support.

  • how much weight can I expect to lose?

    That depends on how closely you follow a reduced-calorie, low-fat diet, get regular physical activity and take alli capsules as directed. alli promotes gradual, modest weight loss of about 1 to 2 pounds a week. If you could lose 10 pounds through dieting, you could lose 15 with alli. Results for each individual may vary.

  • how long can I take alli?

    The alli label does not limit the amount of time you can take alli. You can take it until you achieve the success you want with weight loss. Most weight loss occurs within the first 6 months of using alli.

    If you stop taking alli capsules, continue with your diet and exercise program to help maintain your weight. If you start to regain weight after you stop taking the capsules, you may need to start taking them again along with a diet and exercise program.

  • is Xenical® the same as alli?

    Xenical® and alli contain the same active ingredient (Orlistat), but they are not the same. The products have different indications and dosages. Xenical, manufactured by Roche, is prescription Orlistat, a 120 mg capsule indicated for the treatment of obesity in patients who require the supervision of a physician.

    alli is 60 mg Orlistat, an over-the-counter weight-loss aid for overweight adults who follow a reduced-calorie, low-fat diet. As an FDA-approved OTC aid, alli puts the consumer in control by offering a proven OTC weight-loss aid with comprehensive support.

  • how soon after taking alli capsules should I expect to see results?

    If you follow a reduced-calorie, low-fat diet, get regular physical activity and take alli capsules as directed, you should see results in the first two weeks. Most weight loss usually occurs within the first six months. If you stop using alli, continue with a diet and exercise program for help with weight loss. You may start to regain weight after you stop taking alli. In order to maintain your weight loss, you may need to continue taking alli along with a reduced-calorie, low-fat diet.

  • how do I know if alli is appropriate for my current weight and height?

    To see if alli capsules are right for you, find your height on the chart below. You should only start a weight-loss program with alli if your weight is the same or more than the weight shown for your height.
    
    

  • what can I eat on the alli program?

    When you partner with the alli program, you’ll be able to eat meals that are both healthy and delicious. With the help of our healthy eating guide and interactive meal planner, you’ll find yourself indulging in flavorful meals and snacks every day of the week. And that’s important, because part of your success depends on how well you follow a reduced-calorie, low-fat diet while taking alli capsules as directed.

    The alli program is not about starvation or deprivation; so while it’s important to limit choices that are high in fat and/or calories, you will find that you can still enjoy many of your favorite foods in moderation.

• alli program

  • how does the alli program work?

    alli® is the only FDA-approved, over-the-counter weight-loss aid. But it’s more than just a pill. It’s an innovative weight-loss program.

    The pill works by preventing your body from absorbing some of the fat you eat. The active ingredient in alli attaches to some of the natural enzymes in the digestive system and prevents absorption of about a quarter of the fat you eat. Undigested fat cannot be absorbed and passes through the body naturally. Because alli works only in your digestive tract, it will not affect your heart or brain so you will not experience any racing heart or jitteriness.

    Along with the capsule, the alli program supplies you with a wealth of education, advice and support.

  • how effective is the alli program?

    With alli, you can lose about 50% more weight than with just dieting alone. That means if you could lose 10 pounds through dieting alone, you could lose 15 with alli.

  • if alli capsules only work on the fat in my food, how do I lose the fat in my body?

    As you consume fewer calories on a reduced-calorie, low-fat diet – and use alli to block absorption of some of the fat you eat – your body will automatically tap into its fat stores and use them for the energy it needs. That can result in weight loss.

  • how much weight can I expect to lose?

    That depends on how closely you follow a reduced-calorie, low-fat diet, get regular physical activity and take alli capsules as directed. alli promotes gradual, modest weight loss of about 1 to 2 pounds a week. If you could lose 10 pounds through dieting, you could lose 15 with alli. Results for each individual may vary.

  • how soon after taking alli capsules should I expect to see results?

    If you follow a reduced-calorie, low-fat diet, get regular physical activity and take alli capsules as directed, you should see results in the first two weeks. Most weight loss usually occurs within the first six months. If you stop using alli, continue with a diet and exercise program for help with weight loss. You may start to regain weight after you stop taking alli. In order to maintain your weight loss, you may need to continue taking alli along with a reduced-calorie, low-fat diet.

  • how do I know if alli is appropriate for my current weight and height?

    To see if alli capsules are right for you, find your height on the chart to the right. You should only start a weight-loss program with alli if your weight is the same or more than the weight shown for your height.

  • what can I eat on the alli program?

    When you partner with the alli program, you’ll be able to eat meals that are both healthy and delicious. With the help of our healthy eating guide and interactive meal planner, you’ll find yourself indulging in flavorful meals and snacks every day of the week. And that’s important, because part of your success depends on how well you follow a reduced-calorie, low-fat diet while taking alli capsules as directed.

    The alli program is not about starvation or deprivation; so while it’s important to limit choices that are high in fat and/or calories, you will find that you can still enjoy many of your favorite foods in moderation.

  • should I use a multivitamin with alli?

    Take a multivitamin once a day at bedtime while using alli capsules to ensure adequate absorption of vitamins A, D, E, K and beta-carotene. We recommend Centrum®, a balanced and complete multivitamin.

  • where can I find alli in stores?

    alli is available online and in all major local drug, grocery and discount/warehouse stores in the weight-loss product aisle. If you are buying alli for the first time, choose the alli starter pack, which includes alli capsules, the Shuttle™ carrying case and seven reference guides. For refills, choose the alli refill pack, which includes alli capsules, the Read Me First Guide and the Companion Guide.

  • how is alli different from other weight-loss aids?

    alli is not a dietary supplement. It is an FDA-approved weight-loss aid. Orlistat (the active ingredient in alli) has been extensively studied and safely taken by millions of people worldwide. Americans spend an estimated $33 billion on weight-loss products and programs that in some cases are unregulated and unsafe. The absence of a proven safe and effective OTC aid for weight loss has been a void in the nation’s arsenal of weapons to fight the overweight and obesity epidemic. Orlistat is the only weight-loss aid approved by the FDA to go over-the-counter. Orlistat can help people lose 50% more weight than with dieting alone. That means if you could lose 10 pounds with a diet, you could lose 15 pounds working with alli. Individual results may vary.

  • how effective is alli?

    alli works by blocking the absorption of about 25% of fat in the foods you eat, leading to a 5% to 10% weight loss over time. alli met the rigorous FDA standards for a weight-loss aid. Clinical trials with alli have consistently shown it to be more effective than diet alone. alli can help people lose 50% more weight than with dieting alone. This means that if you could lose 10 pounds with a diet, you could lose 15 pounds working with alli.

  • is there a benefit in losing 5% to 10% of your weight?

    Obesity experts in the U.S. agree and widely available research demonstrates that moderate weight loss is beneficial. It is important to emphasize the health benefits of 5% weight loss and to change the perception of Americans who reject this as an insignificant amount of weight loss. Achievable, realistic weight loss of 5% can result in significant improvements in overall health, including decreased risk for heart disease. Slow, steady weight loss is the healthy way to reduce body fat mass. The alli program encourages the lifestyle changes that help achieve realistic goals of improved health and weight-loss maintenance.

  • the math behind alli does not seem to add up. If the drug in the alli capsule inhibits the absorption of about 25% of the fat that I eat, and I follow the plan, it would take me around 5 weeks to lose 1 pound. How does that equate to 50% more weight loss than dieting alone?

    It is important to remember that alli capsules are not intended to do all of the work for you or to replace diet and exercise. alli is indicated to be taken with a reduced-calorie and low-fat diet.

    Clinical studies have proven that people who followed a reduced-calorie, low-fat diet while taking alli capsules experienced 50% more weight loss than those who just followed the diet. alli capsules (Orlistat 60 mg) prevent the absorption of about 25% of the fat you eat and cause a calorie deficit in your diet. The actual amount of fat blocked by alli is dependent on the total amount of fat consumed. As discussed in the educational materials that are provided in the alli starter pack, individuals will have different total caloric daily needs based on their weight and activity levels.

    In addition, individuals who used alli reported experiencing greater motivation. They were more likely to follow and maintain a low-fat diet while on alli. In addition, they were more likely to exercise.

• use and dosage

  • how does alli work?

    alli works by inhibiting some of the body’s absorption of dietary fat. Taken at meal times, it works by blocking the absorption of about 25% of fat in the foods you eat. Because of the way it works, alli must be used in conjunction with a reduced-calorie, low-fat diet containing about 15 grams of fat per meal. Eating a meal with too much fat while taking alli can result in bowel changes, such as loose stools, more frequent stools that may be hard to control, or gas with oily spotting. These changes, called treatment effects, may occur in the first weeks of treatment, are not harmful and can generally be managed by following a reduced-calorie, low-fat diet that does not exceed 15 grams of fat per meal.

    alli works in the gut; it is nonsystemically acting, which means it does not affect the central nervous system (CNS) and has no effect on the heart or the brain. Some weight-loss drugs and supplements that are systemically absorbed can be associated with CNS side effects (e.g., seizure, stroke and anxiety) or systemic side effects (e.g., heart palpitations, elevated blood pressure and heart problems). alli, a nonsystemic weight-loss aid, is not associated with these side effects, and its safety and efficacy are well established.

  • who can take alli?

    alli can be taken by overweight individuals age 18 or older who are ready to make the change to a reduced-calorie, low-fat diet. But, as with all medicines, there are some people who should not take alli or who need to check with their doctor first, so it is important to review the label before purchasing alli.

    alli has been studied in ethnically diverse populations and has been proven safe and effective for all populations regardless of gender, race and initial weight. Data shows that alli plus diet is always significantly better than diet alone.

  • can children use alli?

    No. alli is indicated for use by overweight individuals 18 years of age or older.

  • how should alli be taken?

    The recommended dose of alli is 1 capsule 3 times a day with meals containing fat. Additionally, to ensure adequate vitamin absorption, those taking alli should also take a multivitamin once a day, at bedtime, because alli may reduce the absorption of fat-soluble vitamins (vitamins A, D, E, K and beta-carotene).

  • Xenical® the same as alli?

    Xenical® and alli contain the same active ingredient (Orlistat), but they are not the same. The products have different indications and dosages. Xenical, manufactured by Roche, is prescription Orlistat, a 120 mg capsule indicated for the treatment of obesity in patients who require the supervision of a physician.

    alli is 60 mg Orlistat, an over-the-counter weight-loss aid for overweight adults who follow a reduced-calorie, low-fat diet. As an FDA-approved OTC aid, alli puts the consumer in control by offering a proven OTC weight-loss aid with comprehensive support.

  • when do I take alli?

    The mealtime dosing schedule (one hour before, during, or one hour after a meal) makes it easy to remember alli capsules. To help you remember, we recommend making alli a part of your pre-meal routine. Once alli and the routine have been paired several times, the association will become automatic. However, if a dose is missed, alli can be taken up to one hour after a meal and still be effective. The alli Shuttle™ carrying case is provided with the alli starter pack to enhance compliance and serve as a helpful reminder to take alli capsules with your meals.

  • if I eat more than 3 meals a day, should additional doses of alli be taken?

    It is recommended that alli be taken with meals – up to 3 times a day. Additional doses are not recommended.

  • if I use alli more than 3 times daily, will I experience better results?

    No. Dose ranging studies show that it is unlikely that higher doses will provide better results. Additional doses are not recommended.

  • how long can I take alli?

    The alli label does not limit the amount of time you can take alli. You can take it until you achieve the success you want with weight loss. Most weight loss occurs within the first 6 months of using alli.

    If you stop taking alli capsules, continue with your diet and exercise program to help maintain your weight. If you start to regain weight after you stop taking the capsules, you may need to start taking them again along with a diet and exercise program.

  • can a person drink alcohol while taking alli?

    Yes. There is no interaction between alli and alcohol. However, alcohol is high in calories. It can, therefore, contribute to weight gain.

  • what should a woman do if she becomes pregnant while taking alli?

    Women who are pregnant or breast-feeding should not take alli. If a woman discovers that she is pregnant while taking alli, she should stop taking the capsules and consult with her physician about appropriate body weight and diet while pregnant or breast-feeding.

  • what happens if alli is taken with a fat-free meal?

    Nothing will happen because there is no fat for alli to inhibit. alli only works locally in the gut on GI lipase activity and does not cause any bowel changes without the consumption of dietary fat.

  • how do I best pick a starting date to begin taking alli?

    Pick the day you will begin taking alli capsules, and start the diet a few days before you begin taking the capsules. If possible, start taking alli capsules on a weekend when you are home.

  • i don’t like to eat breakfast. Can I just pass on that meal?

    Clinical studies show alli works best when you eat 3 healthy, low-fat meals a day, one of which is breakfast. If you skip a meal or you are certain your meal contains no fat, you can skip a dose.

    People who skip breakfast tend to overeat later in the day. There are plenty of quick, satisfying breakfast choices in the alli meal plans.

  • is there a waiting limit between taking 2 capsules?

    The recommended dose of alli is 1 capsule with meals containing fat and no more than 3 capsules daily. alli should be taken within an hour of each meal containing fat. It's best to wait at least 2 hours in between doses. However, it is also best to spread your calories throughout the day in breakfast, lunch and dinner.

  • is dieting necessary while taking alli?

    Yes. A well-balanced, reduced-calorie, low-fat diet containing about 15 grams of fat per meal is recommended while taking alli. These recommendations are consistent with dietary guidelines established by the USDA (total fat intake between 20% to 35% of calories).

    Purchase of alli includes a comprehensive educational support program and an individually tailored, online action plan to help ensure optimal use of alli. Materials include Welcome and Companion Guides, a “Read Me First” Guide, a Guide to Healthy Eating, a Daily Journal, a Calorie & Fat Counter and Quick Facts Cards.

  • can alli be used with diets that are low in carbohydrates and high in fat?

    No. alli is only recommended in conjunction with low-fat diets that contain about 15 grams of fat per meal. Eating a meal with too much fat while taking alli can result in bowel changes, such as loose stools, more frequent stools that may be hard to control or gas with oily spotting. These changes, called treatment effects, may occur in the first weeks of treatment, are not harmful and can be managed by following a reduced-calorie, low-fat diet of no more than 15 grams of fat per meal.

  • what happens if I forget to take alli capsules?

    If you miss a dose, you simply lose the benefit of alli capsules to block absorption of some of the fat in foods you eat for that meal. Resume taking alli at your next meal.

  • does alli begin to work in the stomach, or does it begin to work in the small or large intestines?

    alli does begin to work in the stomach, but the majority of the action occurs in the small intestine.

• safety and drug interactions

  • is alli safe?

    alli has been approved by the FDA as safe and effective when taken according to label directions.

    Taken at mealtime, alli works by blocking the absorption of ¼ of the fat in the foods you eat. alli is nonsystemically acting, which means it does not affect the central nervous system (CNS) and has no effect on the heart or the brain.

    The safety and efficacy of Orlistat are both well established. A higher dose of Orlistat has been marketed as the prescription drug Xenical in the U.S. since 1999 and is supported by nine years of use in 145 countries. Orlistat experience in more than 25 million patient treatments and more than 100 clinical studies with more than 30,000 patients is unprecedented for a weight loss drug. One of these studies was the four-year landmark XENDOS trial conducted by its manufacturer, Roche. This study is the longest study ever conducted for a weight-loss drug.

  • does alli cause any heart racing or palpitations?

    No. alli works in the gut; it is nonsystemically acting, which means it does not affect the central nervous system (CNS) and has no effect on the heart or the brain.

  • what is the rationale behind the label advice for patients with gallbladder disease, pancreatitis and kidney stones to speak with their doctor?

    Obesity puts people at a greater risk for these conditions. If you have a history of any of these conditions, talk to your doctor before using alli.

  • can you take alli if you have had your gallbladder removed?

    If you have had your gallbladder removed, you may have problems absorbing food. Check with the doctor before using alli.

  • can you take alli if you have had gastric bypass surgery?

    If you have had gastric bypass surgery, you should talk with your doctor before taking alli. Some patients experience problems absorbing food after such a procedure. If this is the case, alli may not be right for you. However, everyone handles these procedures differently, so it is best to check with your doctor first.

  • how long does alli remain in your system?

    Since everyone has different GI transit times, the active ingredient in alli can actually remain in your system for up to 48 to 72 hours, mainly because gastric emptying time varies from person to person.

  • will alli interfere with birth control medications?

    No. alli does not impact the efficacy of your birth control medication. A clinical trial using Orlistat (the active ingredient in alli) in 20 normal body weight women taking birth control pills for 23 days found that Orlistat had no effect on the ovulation suppression action of the birth control drug.

  • can you take antibiotics while taking alli?

    Yes. There are no clinically significant drug interactions with antibiotics.

  • if alli prevents the absorption of some of the vitamins I take, will it also block the medication that I take for cholesterol?

    No. It won’t block a cholesterol medication.

  • will alli block any other medications besides those for cholesterol?

    alli may block other medications. Please check the alli label before purchasing alli. Please consult with your healthcare professional.

  • does alli interfere with statins (e.g., Lipitor®, Zocor®, Pravachol®, etc.)?

    No.

  • does alli interfere with bile acid sequestrants such as cholestyramine (Questran®), colestipol (Colestid®) and colesevelam (Welchol®)?

    Since these medications often bind, and therefore inactivate, other drugs given concurrently, it is recommended that you take alli at least 1 hour before or 4 to 6 hours after bile acid sequestrant administration to avoid impeding the effects of alli.

  • do alli and Zetia® work the same way? Can I take them both together?

    Zetia reduces blood cholesterol by inhibiting the absorption of cholesterol in the small intestine. alli, on the other hand, works in the stomach, where it inhibits the action of gastric and pancreatic lipases. Since these two drugs have different mechanisms of action and work at different sites in the body, it is unlikely that there will be an interaction between the two.

  • is it OK for diabetics to use alli?

    Ask a doctor before using alli if you are taking medicines for diabetes. There is no drug interaction between alli and diabetes medications; however, people with diabetes may have lower blood sugar levels and improved glycemic control after losing weight with alli. This may require a dose reduction of their diabetes medication.

  • i am also on hypertensive medications. Will I be able to take alli?

    alli does not interact with hypertensive medications, so it is OK to take alli while taking hypertensive medications. If you have questions, please check with your healthcare professional.

  • can I take alli if I am taking medicine for thyroid disease, e.g., Levoxyl® for hypothyroidism?

    Check with a doctor or pharmacist before taking alli if you are taking medication for thyroid disease. People being treated for thyroid disease may need the dose of their thyroid medication adjusted based on their weight loss.

  • is it safe to take alli with the migraine medications Topamax® and Maxalt®?

    It is safe to take alli with the migraine medications Topamax and Maxalt. But, if you have any medical condition, you should first consult a physician before you change your dietary habits.

  • is alli safe for those taking cyclosporine (Neoral®, Sandimmune®, SangCya®)?

    The label warns consumers in two label sections (organ transplant patients and cyclosporine users) that they should not use alli because it can lower the levels of that drug in the body.

  • is alli safe for those taking cyclosporine eye drops?

    Do not use alli if you are taking cyclosporine. If you have any other questions, check with your doctor first.

  • is alli safe for those taking warfarin (Coumadin®)?

    If you are using warfarin, check with your doctor or pharmacist before taking alli, as you will need to be monitored and may need to have your warfarin dose adjusted.

  • can alli be taken with Benecol®?

    Yes. There has been no interaction identified between the ingredient in Benecol (plant stanol esters) and Orlistat (the active ingredient in alli). On the alli program, you should aim for 15 grams of fat or less from each meal. One serving of Benecol Spread or Benecol Light Spread contains 8 or 5 grams of fat, respectively. Therefore, patients need to be mindful of the contribution of the fat in Benecol to the total amount of fat in the meal.

  • can you take alli if you have irritable bowel syndrome?

    You should first talk to your doctor before purchasing alli if you have IBS. People with IBS have problems absorbing food. Do not use alli if you have problems absorbing food.

  • under what conditions should I not take or stop using alli capsules?

    It’s important to read the alli label before using alli capsules. Be sure you understand the following information:

    Warnings

    Organ transplant alert:

    • do not use if you have had an organ transplant. alli interferes with the medicines used to prevent transplant rejection

    Allergy alert:

    • do not use if you are allergic to any of the ingredients in alli capsules

    Do not use

    • if you are taking cyclosporine
    • if you have been diagnosed with problems absorbing food
    • if you are not overweight

    Ask a doctor before use if you have ever had

    • gallbladder problems
    • kidney stones
    • pancreatitis

    Ask a doctor or pharmacist before use if you are

    • taking warfarin (blood thinning medicine), or taking medicine for diabetes or thyroid disease. Your medication dose may need to be adjusted
    • taking other weight-loss products

    Stop use and ask a doctor if

    • you develop itching, yellow eyes or skin, dark urine or loss of appetite. There have been rare reports of liver injury in people taking orlistat.
    • severe or continuous abdominal pain occurs. This may be a sign of a serious medical condition

    If pregnant or breast-feeding, do not use.

    Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

  • is alli safe for elderly adults?

    alli is indicated for use by overweight consumers 18 years of age or older, including older adults. If you have specific issues or health concerns, please check with your healthcare professional.

• treatment effects or adverse events

  • what are the side effects of alli?

    Most side effects are related to the way you take the product and how much fat you consume when taking alli. Not everyone experiences GI side effects (or “treatment effects”), but they can be manageable when you follow a reduced-calorie, low-fat diet.

    All drugs can have side effects and you should check with your doctor if anything unusual or severe occurs when using any weight-loss product. In controlled trials, only about 5% of subjects on alli dropped out due to treatment effects. In fact, anecdotally, many users have told us that treatment effects served as a signal that helped them adopt healthier eating patterns.

  • will alli affect my sleeping pattern?

    No. alli is nonsystemic acting and won’t affect the central nervous system. You will not feel the same jitteriness or palpitations from the drug.

    There has been no evidence in the clinical trials that indicates that it causes a problem. If you experience sleep problems, please see your doctor.

  • does taking fiber with your diet help to reduce treatment effects?

    There is no conclusive scientific evidence that fiber will reduce the treatment effects of alli, although fiber has many benefits to your body. However, eating a reduced-calorie, low-fat diet will help to manage treatment effects.

  • what about treatment effects?

    Treatment effects are bowel movement changes that are most commonly caused by eating meals with too much fat while using alli capsules. Such effects may include oily spotting, loose stools and more frequent stools that may be hard to control.

    alli works by blocking the absorption of a quarter of the fat in the foods you eat. This undigested fat passes through the body naturally and it is not harmful. In fact, you may recognize it in the toilet as something that looks like the oil on top of a pizza.

    Eating a low-fat diet that consists of 15 grams of fat per meal on average can lower the chance of experiencing these treatment effects.

    Additionally, the alli program can help you reduce the likelihood of having treatment effects. For example, when you purchase alli, you receive educational booklets, which help you transition to a healthy lifestyle. You’ll also receive access to myalliplan™, an individualized, online support program created by weight-loss experts, where you can get recipes and meal plans for low-fat meals.

  • how do I report an adverse event from taking alli capsules?

    To report an adverse event or side effect as a result of using alli capsules, please call 1-800-671-2554, M-F, 9 a.m. – 4:30 p.m. ET so we can give you personalized attention. In the event of a medical emergency, please contact your doctor, local emergency facility, or local poison control center. To report an adverse event directly to the FDA, please call 1-800-FDA-1088.

• dietary fat and alli

  • what is dietary fat?

    Fat has more than twice the calories per gram than carbohydrates or protein (9 calories per 1 gram of fat versus 4 calories per 1 gram of carbs or protein). Dietary fat is the most concentrated source of food energy. Dietary fats are composed chiefly of triglycerides, such as the fat in meats, milk products and vegetable oils. Research attributes health risks to certain kinds of dietary fats. For example, it is believed that saturated fats (e.g., animal fats and butter) may be more dangerous to your health than polyunsaturated (e.g., corn and soybean oils) and monounsaturated fats (e.g., canola and olive oils), which may have a beneficial impact. All fat types, however, have the same number of calories and are affected by alli in the same way.

  • why is it important to target dietary fat?

    Intake of excessive calories can lead to weight gain. Because dietary fat is calorie dense (2 times as much per gram than other nutrients), it can quickly lead to excessive calorie intake and weight gain. Weight gain is one of the major risk factors for conditions leading to heart disease, including high blood pressure, high cholesterol, and diabetes.

  • what can I do to help determine the amount of fat per meal?

    Use the reference booklets in the alli starter pack. The pack includes: Keys to Successful Weight Loss (“Read Me First”), Welcome Guide (“Hi”), Quick Facts Cards, Companion Guide, Healthy Eating Guide, Calorie & Fat Counter, and Daily Journal. The alli program gives you access to a comprehensive support program, including tools to help evaluate dietary fat content.

  • what if I consume a diet containing more than 15 grams of fat per meal?

    alli is recommended for use 3 times daily with meals containing fat. Meals should contain 15 grams of fat or less. Dietary fat consumption beyond the recommended 15 grams of fat per meal may result in an increased incidence of treatment effects, such as loose stools, more frequent stools that may be hard to control, or gas with oily spotting. These changes may occur in the first weeks of treatment, are not harmful and can be managed by following a reduced-calorie, low-fat diet with no more than 15 grams of fat per meal. In comparative trials, only about 3% of subjects on alli dropped out due to treatment effects. In fact, anecdotally, many users reported that treatment effects served as a signal that helped them adopt healthier eating patterns.

  • does alli discriminate between types of fat, or does it prevent the absorption of both good and bad fats?

    alli does not discriminate between types of fat but prevents the absorption of about 25% of fat consumed. But remember, eating too much fat, whether it’s “good” or “bad” fat, can contribute to weight gain and possibly result in treatment effects. You should stay within your fat gram goal for each meal.

  • what about supplements such as vitamin E and flaxseed oil? Should I discontinue or limit them?

    We recommend you take a multivitamin (which contains vitamins A, D, E, K and beta-carotene), at bedtime, while taking alli. If your doctor has recommended taking other supplements, take them as recommended by your doctor. But, remember that these and some other supplements may contain fat, and the supplement will count toward your fat intake targets.

• ingredients

  • does alli contain any nut products?

    There are no nut derivatives or any other food allergens in alli capsules.

  • does alli contain soy?

    Yes. There is soy in the gelatin capsule.

  • are there animal derivatives in alli?

    Yes, the capsule and banding kit both contain components that are derived from bovine origin.

  • does alli contain sulfur?

    Yes. alli may contain trace amounts of sulfur, in the form of sodium lauryl.

  • does alli contain gluten, dairy, shellfish, or caffeine?

    No.

  • does alli contain any pork derivatives?

    Yes, the gelatin of the alli capsule may be of pork origin and is not kosher.

• obesity and BMI

  • what is obesity?

    Obesity can be defined as an excess accumulation of body fat sufficient to endanger health. It is a disease (not a personal weakness) that requires long-term treatment and management to achieve and sustain weight loss.

    Experts agree that the primary cause of obesity is the excessive intake of calories, generally as fat. Obesity results from an imbalance between energy intake and energy output (excess calories consumed, insufficient or decreased physical activity). The correlation between energy intake, expenditure and resulting body fat distribution varies by individual, which is what makes the reasons for this imbalance so unclear. In general, it is easiest for the body to store excess calories if they are consumed in the form of fat. It is harder for the body to convert excess carbohydrates or protein into fat.

    Other factors which are thought to contribute to obesity are genetic, environmental, socioeconomic, cultural and psychological.

  • how is obesity measured?

    The most widely accepted measurement of obesity is known as the Body Mass Index (BMI).

    BMI is calculated by the weight (kg) divided by the height in meters squared.
    The BMI is graded to indicate the degree of risk to health.
    BMI < 18.5 (underweight)
    BMI 18.5-24.9 (desirable weight)
    BMI 25-29.9 (overweight)
    BMI 30-40 (obese)
    BMI > 40 (severely obese)

    Other methods of measuring obesity include:

    • waist circumference – measuring the distribution of abdominal fat, which is well correlated with the risk of developing cardiovascular diseases.
    • height-weight ratio – using an appropriate measurement of frame size – small, medium, large – height/weight tables can be used to estimate ideal weight.
    • measuring percent of body fat – using skinfold test and/or the body impedance method.

  • why does obesity need to be managed?

    Obesity is associated with an increase in serious health risks including:

    • elevated blood pressure and cholesterol levels
    • diabetes (non-insulin dependent diabetes mellitus)
    • some forms of cancer
    • osteoarthritis
    • gallstones
    • respiratory complications, such as increased difficulty in breathing while asleep
    • reduced quality of life

    If you have a question about obesity in your personal health, check with your doctor.

• myalliplan

  • what if want to register with myalliplan but I’m under 18 years of age?

    alli capsules and myalliplan are intended for individuals who are 18 or older. If you are under 18 and have purchased alli, you can contact us or call customer service at 1-877-4myalli (469-2554) M-F, 10 a.m. – 6 p.m. ET.

  • what if I want to register but my Body Mass Index (BMI) is too low?

    If your Body Mass Index is below the healthy range of 18.5-24.9, your body fat level may be low. alli is a weight-loss aid intended for individuals who are overweight. So alli is not right for you.

    You will not be able to complete registration for myalliplan. It’s a good idea to talk with your doctor about reaching a BMI that’s right for your body type. If you would like more information, please contact us or call customer service at 1-800-671-2554 M-F, 9 a.m. – 4:30 p.m. ET.

  • what if I want to register but I have symptoms of an eating disorder?

    If you are currently experiencing symptoms of an eating disorder, you will not be able to complete registration for myalliplan. We suggest you talk with your doctor about your eating habits and your interest in dieting. If you think you may have an eating disorder and you’ve purchased alli, you can contact us [links to CU] or call customer service at 1-800-671-2554, M-F, 9 a.m. – 4:30 p.m. ET.

  • can I use myalliplan without purchasing alli?

    We’re sorry, but myalliplan was designed specifically to work with alli capsules. You will not be able to register with myalliplan without purchasing alli and entering the alli code online. The code is located on the inside cover of the Welcome Guide (also known as the “Hi” Guide), found in the alli starter pack. For the alli refill pack, the code is inside the cover of the Companion Guide.

    You can use alli capsules without using myalliplan. But this is not recommended. Keep in mind that this plan was developed by clinical weight-loss experts to provide you the feedback and guidance necessary to help you succeed. The power of the alli program is the combination of both the FDA-approved pill with the individually tailored plan.

  • how do I complete my first myalliplan check-in?

    In order to help ease you into myalliplan, the alli 1-2-3 Start Plan was created to give daily tips and lessons on how to begin taking alli and to introduce you to myalliplan. This plan is a 10-day program that you will complete before your first check-in.

    On the last day of your Start Plan program, you will be able to complete your first check-in. There will be a button to “check in now” in the “Your 1-2-3 Start Plan Lesson” box on your myalliplan home page. From here you will be able to enter your weight, fill out a brief survey about your past week on alli, and you will receive your next weekly step and action plan.

    The results from your weigh-in and survey will be displayed as charts in your “my progress” section of your myalliplan home page. You will not actually enter information into this area, but if needed, you do have the option to edit past check-in weights in your weight chart. Please note: your “activity” tab will not contain a chart until an activity question is included in your survey.

    Your future check-ins will be on the day (Mon.-Sun.) you selected during registration, beginning the following week (a check-in will be not be scheduled within 7 days of a previous check-in).

  • Where can I download more journal pages?

    You can download by clicking here.

• miscellaneous

  • how much does alli cost?

    Generally, the cost is roughly what one might expect to pay for a bag of chips and a can of soda every day – the equivalent of an afternoon snack.

  • how much exercise do you recommend while taking alli?

    You don’t have to hit the gym or hire a personal trainer to make a real difference in your health. Studies show that moderate exercise – such as walking for 30 minutes every day – can reduce your risk for disease.

    The great thing about exercise is its cumulative effect – you don’t have to do it all at once. You can add it to your activities throughout the day by sneaking in a little extra walking to the things you already do.

    What’s important is including activity regularly in your routine. Start small and work your way up. Consistency is your goal.

  • what is the difference between the “Are you losing it?” book and “The alli Diet Plan”?

    The “Are you losing it?” book educates people about a realistic mind-set, healthy weight-loss strategies and a sensible approach to losing weight and keeping it off. The book is a tool to expose myths and obstacles that discourage weight loss, give advice on lifestyle and behavioral changes, provide low-fat menu ideas and offer physical activity tips. The book also includes an overview of alli, the only FDA-approved, over-the-counter weight-loss aid. It is sold near the pharmacy counter of participating stores.

    “The alli Diet Plan” contains recipes and tools helpful while you follow the alli program. The book moves dieters through three phases, each with the same caloric intake but different levels of fat content. The tools include more than 200 delicious, alli-friendly recipes, including no-cook, quick and easy and prepare-ahead options; a restaurant guide with 100 restaurants; a low-intensity, fat-burning fitness program to help you achieve results; and 300 daily menus/meal plans.

  • i have looked at my local store, and I can’t find alli on shelves. What should I do?

    We are sorry to learn that you have found it difficult to locate alli in your area. Please be assured that we are working diligently to ensure that alli is available as quickly as possible.

    Participating grocery, drug and mass retailers, as well as some online retailers, sell alli. If you cannot find alli in one store, you should check another local retailer or go online.

    Additionally, you might wish to order our product online from leading retailers. They can ship the product directly to you.

  • I have been reading “The alli Diet Plan” book. I noticed that there are differences between the information provided in the book and the information in the alli starter pack books. Why is that?

    “The alli Diet Plan” book was written by Dr. Carolyn Apovian and published by Meredith Publishing. The book has a three-phased approach. The approach moves from Phase 1 (15% of your calories from fat) to Phase 3 (30% of your calories from fat). This plan was independently developed by Dr. Apovian to minimize treatment effects.

    “The alli Diet Plan” is compatible with alli. It does follow the same calorie targets as the information provided in the alli materials, but the Phase 1 and Phase 2 fat targets are slightly lower.

  • why are you recommending people take alli with a multivitamin? Does it deplete vitamin levels?

    It’s always sensible advice to take a multivitamin when you are on any kind of weight-loss program. alli works by preventing absorption of about 25% of fat, and it will also minimally inhibit fat-soluble vitamins to the same extent. The fat-soluble vitamins are vitamins A, D, E, K and beta-carotene.

    We recommend that you take a multivitamin with alli, once a day at bedtime.

  • what are the different sizes that alli is available in?

    alli is available in four sizes: 60 ct., 90 ct., 120 ct. and 150 ct. The 60 ct., 90 ct. and 150 ct. are all starter kits. This means that they contain all of the in-pack materials. The 120 ct. is a refill pack and only contains the Companion Guide and the Read Me First guide. Additionally, the 150 ct. is available at club/warehouse stores.

  • what materials are available in Spanish?

    The tools available include:

    • mialli.com, our comprehensive Spanish language web site that includes culturally relevant recipes and advice from health experts
    • a bilingual 1-800 number (1-877-469-2554) consumers can call with questions about the program
    • bilingual support in-store, including our bilingual product brochure and a 2-week bilingual alli meal plan available at pharmacies

    For people who are ready to commit to the program and purchase an alli starter pack, they may also call our 1-800 number to request a full set of the alli in-pack educational materials and the offline alli behavioral support program in Spanish.

    The alli program provides practical support to all consumers willing to embrace a healthier lifestyle.

  • has alli been tested among African Americans and Hispanics?

    The safety and efficacy of alli are well established, and clinical trials with Orlistat (the active ingredient in alli) have consistently shown it to be more effective than diet alone. It can aid weight loss in individuals who are committed to losing weight, regardless of ethnicity.

    The population at large, including African Americans and Hispanics, has been shown to achieve weight loss when committed to the program.

• myalliplangold payment questions

  • When is my Credit Card going to be charged?

    An automatic recurring payment will be made every month after your 30 day trial on a recurring basis. You will also receive a post-payment confirmation email following all automatic recurring payments. For example, if your free trial period ends on March 1, the first recurring monthly payment of $9.99 will be made on March 1. Your next automatic recurring payment in the amount of $9.99 would occur on April 1. You will not receive any advance notice of this payment but you will receive post-payment confirmation by email.

  • Automatic Recurring Payment Failure.

    If your automatic recurring payment is declined, you will be contacted by phone or email. REMEMBER: If your automatic recurring payment fails, you will need to replenish your account with another payment method. In the event any payment is not made and you do not make a payment by the end of your billing cycle, your access to the GOLD sections will be revoked.

  • Cancellation of Automatic Recurring Payment.

    You have the right to withdraw your consent to this Automatic Recurring Payment at any time. To cancel your automatic recurring payment, call Customer Care at 877-469-2554.

  • Reestablishing Automatic Recurring Payment.

    If you wish to reestablish your automatic recurring payment, call Customer Care at 877-469-2554.

  • Changing Automatic Recurring Payment.

    If you would like to change your automatic recurring payment including, for example, making a change from one credit or debit card that was initially selected to another credit or debit card or bank account, you must authorize the recurring payment with the new credit or debit card or bank account by calling Customer Care at 877-469-2554.