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how does alli work?

it works in your digestive system,
not in your heart or brain.


alli in the body

You’re probably curious about what alli® does in your body. The active ingredient in alli attaches to some of the natural enzymes in the digestive system, preventing them from breaking down about a quarter of the fat you eat. Undigested fat cannot be absorbed and passes through the body naturally. The excess fat is not harmful. In fact, you may recognize it in the toilet as something that looks like the oil on top of a pizza.

Because of the way in which alli works, eating meals with too much fat may cause side effects known as treatment effects. Learn more about treatment effects now.

alli only works on enzymes that break down fat, not on other enzymes. So carbohydrates and proteins are not affected. You still absorb those nutrients. But, since fat grams have more than twice as many calories as carbs and proteins, alli capsules work on the worst offenders - the calorie-dense fat grams.

alli is safe when used as directed - it works only in your digestive system, not in your heart or brain. That means you won't feel:

  • jittery effects
  • sleeplessness
  • a racing heart 

Partner with a registered dietitian to start your weight-loss plan

The alli program focuses on making a lifestyle change that includes healthy eating habits. However, you don’t have to make these changes alone. For assistance in finding a Registered Dietitian, visit the American Dietetic Association website.

Recently, the ADA welcomed GlaxoSmithKline Consumer Healthcare, the creators of alli, as an ADA Partner in their corporate relations sponsorship program. Learn more about this partnership.

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eat the food you love with alli
need help? find answers to your questions about alli.